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Profound neuronal differences during Exercise-Induced Hypoalgesia between athletes and non-athletes revealed by functional near-infrared spectroscopy

This functional near-infrared spectroscopy (fNIRS) dataset investigates neuronal mechanisms underlying exercise-induced hypoalgesia in endurance athletes versus non-athletes. Twenty-two athletes and twenty non-athletes performed high-intensity interval training (HIIT) while brain oxygenation was monitored across pain-processing regions including the prefrontal cortex, sensorimotor cortices, and posterior parietal cortex. The study reveals distinct neural activation patterns and pain reduction responses between groups, with athletes demonstrating greater oxyhemoglobin increases in the posterior parietal cortex during exercise and significant post-HIIT decreases in pain perception correlated with prefrontal cortex deactivation.

Participants: 42
Size: 5.51 GB
Version: v1.0.0
Updated: Jun 18, 2026

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